Achalasia is a serious condition that affects your esophagus the lower esophageal sphincter les is a muscular ring that closes off the esophagus from the stomach. In developed countries achalasia of the cardia is diagnosed manometrically by complete absence of primary peristalsis of the oesophageal body failure of the los to relax and elevated los pressure and pressurisation of the oesophagus both in approximately 50 of cases. Achalasia cardia is one of the common causes of motor dysphagia though the disease was first described more than 300 years ago exact pathogenesis of this condition still remains enigmatic pathophysiologically achalasia cardia is caused by loss of inhibitory ganglion in the myenteric plexus of the esophagus. Achalasia is a rare disorder that makes it difficult for food and liquid to pass into your stomach achalasia occurs when nerves in the tube connecting your mouth and stomach esophagus become damaged
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